SCHEMBL8922380

SCHEMBL8922380

Cc1ccc(C2CC(N)C(=O)N(CC(=O)NC(C)(C)C)c3ccccc32)cc1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8398479 0.93 CCKBR (0.64) CCKBR
SCHEMBL8919504 0.91 CCKBR (0.56) CCKBR
SCHEMBL8919215 0.91 CCKBR (0.67) CCKBR
SCHEMBL8402111 0.88 CCKBR (0.65) CCKBR
SCHEMBL8924403 0.88 CCKBR (0.64) CCKBR
SCHEMBL8919676 0.87 CCKBR (0.57) CCKBR
SCHEMBL9541664 0.85 CCKBR (0.48) CCKBR
SCHEMBL8921951 0.85 CCKBR (0.51) CCKBR
SCHEMBL8922596 0.85 CCKBR (0.71) CCKBR
SCHEMBL8920664 0.82 CCKBR (0.95) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5643904-A Substituted hexahdryoazepinones and tetrahydrobenzazepinones PFIZER INC. (US) 1997-07-01 US disclosed
US-5484917-A FOR TREATMENT AND PREVENTION OF GASTROINTESTINAL DISORDERS, PAIN AND ANXIETY PFIZER INC. (US) 1996-01-16 US disclosed