Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 18/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919215 | 0.90 | CCKBR (0.67) | CCKBR | |
| SCHEMBL8922596 | 0.89 | CCKBR (0.71) | CCKBR | |
| SCHEMBL8398479 | 0.87 | CCKBR (0.64) | CCKBR | |
| SCHEMBL8922380 | 0.87 | CCKBR (0.66) | CCKBR | |
| SCHEMBL8919504 | 0.86 | CCKBR (0.56) | CCKBR | |
| SCHEMBL9542930 | 0.85 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8921286 | 0.82 | CCKBR (0.68) | CCKBR | |
| SCHEMBL8921951 | 0.82 | CCKBR (0.51) | CCKBR | |
| SCHEMBL8921306 | 0.81 | CCKBR (0.81) | CCKBR | |
| SCHEMBL8921298 | 0.81 | CCKBR (0.52) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643904-A | Substituted hexahdryoazepinones and tetrahydrobenzazepinones | PFIZER INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5484917-A | FOR TREATMENT AND PREVENTION OF GASTROINTESTINAL DISORDERS, PAIN AND ANXIETY | PFIZER INC. (US) | 1996-01-16 | — | — | US | disclosed |