Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.63 |
| ▸ | KMO | O15229 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30241132 | 0.90 | AKR1C3 (0.66) | AKR1C3KMONPC1POLBCYP2C9 | |
| SCHEMBL1636273 | 0.90 | AKR1C3 (0.66) | AKR1C3KMONPC1POLBCYP2C9 | |
| SCHEMBL8922344 | 0.90 | SRD5A2 (0.53) | AKR1C3KMONPC1POLBCYP2C9 | |
| SCHEMBL5552784 | 0.88 | AKR1C3 (0.67) | AKR1C3KMONPC1POLBCYP2C9 | |
| SCHEMBL16429183 | 0.87 | AKR1C3 (0.62) | AKR1C3KMONPC1POLBCYP2C9 | |
| SCHEMBL29420736 | 0.85 | SRD5A2 (0.57) | AKR1C3KMOCYP2C9MRGPRX4NR4A2 | |
| SCHEMBL545227 | 0.85 | SRD5A2 (0.57) | AKR1C3KMOCYP2C9MRGPRX4NR4A2 | |
| SCHEMBL1100529 | 0.82 | POLB (0.51) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL29779713 | 0.82 | POLB (0.51) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL68858 | 0.82 | AKR1C3 (0.92) | AKR1C3KMONPC1POLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670084-A | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0708149-A1 | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-24 | — | — | EP | disclosed |