SCHEMBL545227

SCHEMBL545227

O=C(O)c1cccc(C(c2cccc(C(=O)O)c2)(C(F)(F)F)C(F)(F)F)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.57
CES2 O00748 1/20 0.53
AKR1C3 P42330 1/20 0.49
AKR1C2 P52895 1/20 0.49
UNG P13051 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA6 P23280 1/20 0.48
CA9 Q16790 1/20 0.48
ACHE P22303 1/20 0.47
MRGPRX4 Q96LA9 2/20 0.47
NR4A2 P43354 1/20 0.47
KIF11 P52732 1/20 0.46
LMNA P02545 1/20 0.46
KMO O15229 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29420736 1.00 SRD5A2 (0.57) SRD5A2CES2AKR1C3AKR1C2UNG
SCHEMBL8922389 0.85 AKR1C3 (0.63) SRD5A2AKR1C3MRGPRX4NR4A2KMO
SCHEMBL5115473 0.85 SRD5A2 (0.62) SRD5A2CES2AKR1C3AKR1C2UNG
SCHEMBL40186 0.84 SRD5A2 (0.77) SRD5A2CES2AKR1C3AKR1C2MRGPRX4
SCHEMBL29433907 0.84 SRD5A2 (0.77) SRD5A2CES2AKR1C3AKR1C2MRGPRX4
SCHEMBL4613288 0.84 SRD5A2 (0.61) SRD5A2CES2AKR1C3AKR1C2UNG
SCHEMBL25955784 0.84 SRD5A2 (0.43) SRD5A2CES2AKR1C3AKR1C2UNG
SCHEMBL8775382 0.83 CES2 (0.52) SRD5A2CES2ACHELMNAHPGD
Hydrochloric Acid SCHEMBL10387616 0.82 SRD5A2 (0.74) SRD5A2CES2AKR1C3AKR1C2MRGPRX4
Hydrochloric Acid SCHEMBL30596522 0.82 SRD5A2 (0.74) SRD5A2CES2AKR1C3AKR1C2MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 571 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035512-A1 POLYAMIDES AND CORRESPONDING POLYMER COMPOSITIONS, ARTICLES AND METHODS FOR MAKING AND USING SYENSQO SPECIALTY POLYMERS USA, LLC (US) 2026-02-05 US claimed
US-12473402-B2 Polyamides and corresponding polymer compositions, articles and methods for making and using SYENSQO SPECIALTY POLYMERS USA, LLC (US) 2025-11-18 US claimed
EP-4276136-B1 POLYAMIDES AND CORRESPONDING POLYMER COMPOSITIONS, ARTICLES AND METHODS FOR MAKING AND USING SYENSQO SPECIALTY POLYMERS USA LLC (US) 2025-11-12 EP claimed
EP-4633909-A1 OVERMOLDED PLASTIC ARTICLES, USES THEREOF, METHOD OF MAKING Syensqo Specialty Polymers USA, LLC (US) 2025-10-22 EP claimed
US-12378357-B2 Polyamides and corresponding polymer compositions and articles SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2025-08-05 US claimed
US-12247099-B2 Process for preparing particles of polyphenylene sulfide polymer SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2025-03-11 US claimed
WO-2024125972-A1 OVERMOLDED PLASTIC ARTICLES, USES THEREOF, METHOD OF MAKING SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2024-06-20 WO claimed
US-20240182635-A1 PROCESS FOR PREPARING PARTICLES OF POLYPHENYLENE SULFIDE POLYMER SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2024-06-06 US claimed
US-11905364-B2 Process for preparing particles of polyphenylene sulfide polymer SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2024-02-20 US claimed
EP-3559081-B1 GLYCOLIC ACID POLYMER SOLVAY (BE) 2023-11-22 EP claimed
WO-2021037850-A1 POLYAMIDES AND CORRESPONDING POLYMER COMPOSITIONS, ARTICLES AND METHODS FOR MAKING AND USING SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-03-04 WO claimed
WO-2020229318-A1 POLYAMIDES AND CORRESPONDING POLYMER COMPOSITIONS AND ARTICLES SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2020-11-19 WO claimed
US-20200190255-A1 GLYCOLIC ACID POLYMER SYENSQO SA (BE) 2020-06-18 US claimed
EP-3559081-A1 GLYCOLIC ACID POLYMER Solvay SA (BE) 2019-10-30 EP claimed
WO-2018115008-A1 GLYCOLIC ACID POLYMER SOLVAY SA (BE) 2018-06-28 WO claimed
US-20160108174-A1 POLYAMIDES COMPRISING ME-BHT, COMPOSITIONS COMPRISING SUCH A POLYAMIDE, SHAPED ARTICLES COMPRISING SUCH A POLYAMIDE OR SUCH A COMPOSITION PERFORMANCE POLYAMIDES, SAS (FR) 2016-04-21 US claimed
EP-3004210-A1 POLYAMIDES COMPRISING ME-BHT, COMPOSITIONS COMPRISING SUCH A POLYAMIDE, SHAPED ARTICLES COMPRISING SUCH A POLYAMIDE OR SUCH A COMPOSITION Rhodia Opérations S.A.S. (FR) 2016-04-13 EP claimed
WO-2014191303-A1 POLYAMIDES COMPRISING ME-BHT, COMPOSITIONS COMPRISING SUCH A POLYAMIDE, SHAPED ARTICLES COMPRISING SUCH A POLYAMIDE OR SUCH A COMPOSITION RHODIA OPERATIONS (FR) 2014-12-04 WO claimed
EP-0397022-A2 Polyimide-Polyamide polymers having fluorine-containing linking groups HOECHST CELANESE CORPORATION (US) 1990-11-14 EP claimed
US-4962183-A HEAT, OXIDATION AND SOLVENT RESISTANCE; MOLDING MATERIALS; MELT PROCESSIBILITY; FIBERS, FILMS AND SHEETS HOECHST CELANESE CORP. (US) 1990-10-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035512-A1 POLYAMIDES AND CORRESPONDING POLYMER COMPOSITIONS, ARTICLES AND METHODS FOR MAKING AND USING ABHD6, DDC, SLC16A8 SRD5A2 4007/4885CES2 591/4885AKR1C3 2320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.