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SCHEMBL8922396

SCHEMBL8922396

CCOC(=O)CC(CC(=O)OCC)(NC(CCC(=O)O)Cc1ccc(-c2ccccc2)cc1)P(=O)(O)O

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 6/20 0.49
▸ MMEL1 Q495T6 1/20 0.43
▸ ACE P12821 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8922371 1.00 MME (0.49) MMEMMEL1ACE
SCHEMBL8921959 0.90 MMEL1 (0.48) MMEMMEL1
SCHEMBL8921943 0.90 MMEL1 (0.48) MMEMMEL1
SCHEMBL7343794 0.84 MMEL1 (0.52) MMEL1
SCHEMBL7413316 0.84 MME (0.46) MMEACE
SCHEMBL7413308 0.84 MME (0.46) MMEACE
SCHEMBL7414211 0.81 MEN1 (0.43) MMEL1ACE
SCHEMBL7414204 0.81 MEN1 (0.43) MMEL1ACE
SCHEMBL7411695 0.81 MME (0.60) MMEMMEL1ACE
SCHEMBL7411683 0.81 MME (0.60) MMEMMEL1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0660840-B1 PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES CIBA GEIGY AG (CH) 1997-05-07 — — EP disclosed
US-5550119-A ENDOTHELIN-CONVERTING ENZYM INHIBITORS CIBA-GEIGY CORPORATION (US) 1996-08-27 — — US disclosed
EP-0660840-A1 PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES. CIBA GEIGY AG (CH) 1995-07-05 — — EP disclosed
WO-1994005677-A1 PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES CIBA-GEIGY AG (CH) 1994-03-17 — — WO disclosed