Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 10/20 | 0.46 |
| ▸ | ACE | P12821 | 9/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.46 |
| ▸ | CPA1 | P15085 | 8/20 | 0.45 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.42 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EED | O75530 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413308 | 1.00 | MME (0.46) | MMEACEACE2CPA1SRR | |
| SCHEMBL7414204 | 0.89 | MEN1 (0.43) | ACEEEDITGB3ITGAV | |
| SCHEMBL7414211 | 0.89 | MEN1 (0.43) | ACEEEDITGB3ITGAV | |
| SCHEMBL8921641 | 0.89 | MME (0.45) | MMEITGB3ITGAV | |
| SCHEMBL8923019 | 0.89 | ITGA4 (0.52) | — | |
| SCHEMBL8921663 | 0.89 | MME (0.45) | MMEITGB3ITGAV | |
| SCHEMBL8923071 | 0.89 | ITGA4 (0.52) | — | |
| SCHEMBL7343794 | 0.87 | MMEL1 (0.52) | L3MBTL1 | |
| SCHEMBL7408527 | 0.87 | MME (0.46) | MMEACEACE2CPA1 | |
| SCHEMBL7408516 | 0.87 | MME (0.46) | MMEACEACE2CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660840-B1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | claimed |
| EP-0660840-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES. | CIBA GEIGY AG (CH) | 1995-07-05 | — | — | EP | claimed |
| WO-1994005677-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1994-03-17 | — | — | WO | claimed |
| US-5250522-A | Neutral endopeptidase inhibitors; cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1993-10-05 | — | — | US | claimed |
| EP-0660840-B1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | disclosed |
| US-5550119-A | ENDOTHELIN-CONVERTING ENZYM INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0660840-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES. | CIBA GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994005677-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1994-03-17 | — | — | WO | disclosed |
| US-5250522-A | Neutral endopeptidase inhibitors; cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |