Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM5A | P29375 | 2/20 | 0.57 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.57 |
| ▸ | ASPH | Q12797 | 2/20 | 0.57 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.57 |
| ▸ | KDM4A | O75164 | 2/20 | 0.57 |
| ▸ | KDM5C | P41229 | 2/20 | 0.57 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.57 |
| ▸ | KDM6B | O15054 | 1/20 | 0.57 |
| ▸ | TET3 | O43151 | 1/20 | 0.57 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.57 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.57 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.57 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.57 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.57 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.57 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31044613 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| SCHEMBL22031705 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| SCHEMBL3535357 | 0.82 | ADORA3 (0.42) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| Water SCHEMBL347466 | 0.82 | KDM4C (0.55) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| SCHEMBL5936390 | 0.82 | KDM4C (0.55) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| SCHEMBL17172500 | 0.79 | KDM4E (0.52) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| SCHEMBL1202476 | 0.79 | KDM4E (0.52) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| SCHEMBL7814231 | 0.78 | P2RX7 (0.46) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| SCHEMBL2783341 | 0.77 | KMT2A (0.43) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| SCHEMBL3054623 | 0.77 | KMT2A (0.51) | KDM4EALDH1A1MAPTNAPRTP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |