Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922510 | 0.84 | SMN1; SMN2 (0.49) | ACESMN1; SMN2MMP8MAPTNPC1 | |
| SCHEMBL1856485 | 0.82 | SMN1; SMN2 (0.51) | ACESMN1; SMN2MMP8TSHRMAPT | |
| SCHEMBL4008125 | 0.76 | SMN1; SMN2 (0.49) | ACESMN1; SMN2MMP8TSHRMAPT | |
| SCHEMBL7423179 | 0.75 | MEN1 (0.46) | SMN1; SMN2CTSKCTSSNPC1 | |
| SCHEMBL3991999 | 0.73 | SMN1; SMN2 (0.48) | ACESMN1; SMN2MMP8MAPTNPC1 | |
| SCHEMBL29269490 | 0.72 | CTSK (0.50) | SMN1; SMN2CTSKCTSSTSHR | |
| SCHEMBL29269488 | 0.72 | CTSK (0.50) | SMN1; SMN2CTSKCTSSTSHR | |
| SCHEMBL10725308 | 0.72 | CTSK (0.55) | ACESMN1; SMN2CTSKCTSSTSHR | |
| SCHEMBL10829369 | 0.72 | ACE (0.56) | ACESMN1; SMN2 | |
| SCHEMBL10603596 | 0.72 | ACE (0.56) | ACESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |