Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 3/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923694 | 0.91 | PDK1 (0.51) | PDK1THRATHRBXDHPLA2G4B | |
| SCHEMBL8923686 | 0.91 | PDK1 (0.51) | PDK1THRATHRBXDHPLA2G4B | |
| SCHEMBL7169538 | 0.91 | PDE4A (0.51) | PDK1THRATHRBXDHPLA2G4B | |
| SCHEMBL7169143 | 0.91 | PDE4A (0.51) | PDK1THRATHRBXDHPLA2G4B | |
| SCHEMBL7169542 | 0.91 | PDE4A (0.51) | PDK1THRATHRBXDHPLA2G4B | |
| SCHEMBL7169145 | 0.91 | PDE4A (0.51) | PDK1THRATHRBXDHPLA2G4B | |
| SCHEMBL8176758 | 0.91 | PDE4A (0.51) | PDK1THRATHRBXDHPLA2G4B | |
| Hydrochloric Acid SCHEMBL8922736 | 0.90 | PDE4A (0.50) | PDK1THRATHRBXDHPLA2G4B | |
| Hydrochloric Acid SCHEMBL8922741 | 0.90 | PDE4A (0.50) | PDK1THRATHRBXDHPLA2G4B | |
| SCHEMBL7168020 | 0.89 | ERN1 (0.46) | PDK1THRATHRBXDHPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658493-A | Ferroelectric liquid crystals for nonlinear optics applications | UNIVERSITY RESEARCH CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| US-5637256-A | Ferroelectric liquid crystals for nonlinear optics applications | UNIVERSITY RESEARCH CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| US-5543078-A | A CHIRAL NONRACEMIC COMPOUND | UNIVERSITY RESEARCH CORPORATION (US) | 1996-08-06 | — | — | US | disclosed |
| WO-1992020058-A2 | FERROELECTRIC LIQUID CRYSTALS FOR NONLINEAR OPTICS APPLICATIONS | UNIVERSITY RESEARCH CORPORATION (US) | 1992-11-12 | — | — | WO | disclosed |