Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923694 | 1.00 | PDK1 (0.51) | PDK1THRATHRBPLA2G4BESR1 | |
| SCHEMBL8922732 | 0.91 | PDK1 (0.45) | PDK1THRATHRBPLA2G4BESR1 | |
| SCHEMBL8924063 | 0.90 | PLA2G4B (0.59) | PDK1THRATHRBPLA2G4BESR1 | |
| SCHEMBL7692420 | 0.90 | PLA2G4B (0.59) | PDK1THRATHRBPLA2G4BESR1 | |
| SCHEMBL7692418 | 0.90 | PLA2G4B (0.59) | PDK1THRATHRBPLA2G4BESR1 | |
| SCHEMBL8924201 | 0.88 | ALDH1A1 (0.48) | PDK1THRATHRBPLA2G4BESR1 | |
| SCHEMBL8183362 | 0.87 | ALDH1A1 (0.52) | PDK1THRATHRBPLA2G4BESR1 | |
| SCHEMBL8183369 | 0.87 | ALDH1A1 (0.52) | PDK1THRATHRBPLA2G4BESR1 | |
| SCHEMBL28748751 | 0.86 | PDK1 (0.57) | PDK1GAAHPGDHCAR3PRSS1 | |
| SCHEMBL8507535 | 0.84 | PLA2G4B (0.46) | PDK1THRATHRBPLA2G4BESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658493-A | Ferroelectric liquid crystals for nonlinear optics applications | UNIVERSITY RESEARCH CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| US-5637256-A | Ferroelectric liquid crystals for nonlinear optics applications | UNIVERSITY RESEARCH CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| US-5543078-A | A CHIRAL NONRACEMIC COMPOUND | UNIVERSITY RESEARCH CORPORATION (US) | 1996-08-06 | — | — | US | disclosed |
| WO-1992020058-A2 | FERROELECTRIC LIQUID CRYSTALS FOR NONLINEAR OPTICS APPLICATIONS | UNIVERSITY RESEARCH CORPORATION (US) | 1992-11-12 | — | — | WO | disclosed |