Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924469 | 0.88 | KDM4E (0.48) | KDM4ESMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL10048132 | 0.88 | GABRA1 (0.47) | PARGKDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL10084475 | 0.86 | HSD17B10 (0.47) | PARGKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL31160820 | 0.85 | KMT2A (0.53) | PARGKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL31161048 | 0.85 | CA9 (0.55) | PARGALDH1A1KMT2APKMCA12 | |
| SCHEMBL31160949 | 0.81 | PARG (0.43) | PARGKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3312291 | 0.81 | CYP1A2 (0.61) | KDM4ESMN1; SMN2ALDH1A1HPGDGLA | |
| SCHEMBL32680072 | 0.81 | CYP1A2 (0.61) | KDM4ESMN1; SMN2ALDH1A1HPGDGLA | |
| SCHEMBL5712351 | 0.79 | CYP1A2 (0.62) | PARGKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL6397114 | 0.79 | MAPT (0.52) | KDM4ESMN1; SMN2ALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693637-A | Bicycle derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |