Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | HPGD | P15428 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 12/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922778 | 0.88 | PARG (0.45) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL7102682 | 0.80 | ADORA2B (0.48) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL8926182 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL10048132 | 0.78 | GABRA1 (0.47) | KDM4EALDH1A1HSD17B10KMT2ASMN1; SMN2 | |
| SCHEMBL5712351 | 0.77 | CYP1A2 (0.62) | KDM4EALDH1A1HPGDKMT2APKM | |
| SCHEMBL6397114 | 0.77 | MAPT (0.52) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL2775966 | 0.74 | CA12 (0.57) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL8924871 | 0.74 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL10084475 | 0.73 | HSD17B10 (0.47) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL31160820 | 0.72 | KMT2A (0.53) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693637-A | Bicycle derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |