SCHEMBL8922833

SCHEMBL8922833

CC(C)(C)c1cc(O)cc(Cc2cc(O)cc(C(C)(C)C)c2O)c1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.68
CYP2C9 P11712 6/20 0.66
CYP2C19 P33261 5/20 0.66
HIF1A Q16665 5/20 0.66
SMN1; SMN2 Q16637 5/20 0.66
CYP2D6 P10635 3/20 0.58
HSD17B10 Q99714 2/20 0.58
CA2 P00918 3/20 0.48
CA1 P00915 2/20 0.48
ALDH1A1 P00352 6/20 0.46
TYR P14679 2/20 0.46
POLB P06746 1/20 0.46
ALOX15 P16050 4/20 0.43
LMNA P02545 3/20 0.43
HTT P42858 2/20 0.43
NR1I2 O75469 1/20 0.43
MIF P14174 1/20 0.43
NFE2L2 Q16236 1/20 0.43
TP53 P04637 2/20 0.43
TSHR P16473 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11410023 0.91 CYP2C9 (0.83) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL28404083 0.85 HSPA5 (0.56) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL11675110 0.83 HSPA5 (0.48) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL39962 0.81 CA2 (0.70) CYP2C9CYP2C19HIF1ASMN1; SMN2CYP2D6
SCHEMBL31332412 0.81 HSPA5 (0.50) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29351672 0.81 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29500375 0.81 HSPA5 (0.66) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL39554 0.81 HSPA5 (0.66) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL30903568 0.81 HSPA5 (0.66) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29415372 0.81 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330504-B1 Photosensitive material and image forming method CANON KK (JP) 1996-05-22 EP claimed
US-5663032-A NAPHTHOL DERIVATIVE REDUCING AGENT CANON KABUSHIKI KAISHA (JP) 1997-09-02 US disclosed
EP-0332455-B1 Photosensitive material and image forming method CANON KK (JP) 1996-06-05 EP disclosed
EP-0330504-B1 Photosensitive material and image forming method CANON KK (JP) 1996-05-22 EP disclosed
EP-0360014-B1 Photosensitive material and image forming method using same CANON KK (JP) 1996-01-03 EP disclosed
EP-0653680-A2 Photosensitive composition, photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-05-17 EP disclosed
US-5415974-A Silver halide, organic silver salt, polymerizable compound, heat-diffusing dye CANON KABUSHIKI KAISHA (JP) 1995-05-16 US disclosed
US-5260164-A Silver halide, organic silver salt, cyclic reducing agent, the above compounds adapted to provide imagewise oxidized product of reducing agent upon imagewise exposure and heat development, polymer precursor, photopolymerization initiator CANON KABUSHIKI KAISHA (JP) 1993-11-09 US disclosed
US-5064744-A Heat, photopolymerization, silver halide contrast CANON KABUSHIKI KAISHA (JP) 1991-11-12 US disclosed
US-5041369-A Silver Halide, Silver Salt, Reducing Agent, Metal or Organic Dye CANON KABUSHIKI KAISHA (JP) 1991-08-20 US disclosed