SCHEMBL8922914

SCHEMBL8922914

Cc1cccc2c1C1(NC2=N)OCCO1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.35
PARP1 P09874 1/20 0.33
PARP10 Q53GL7 1/20 0.33
PARP11 Q9NR21 1/20 0.33
CDK2 P24941 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8919799 0.80 NSD2 (0.35) DAO
SCHEMBL8922917 0.79 DAO (0.31) DAO
SCHEMBL8920911 0.76 DDB1 (0.33)
SCHEMBL8919955 0.76 ALDH1A1 (0.36) ALDH1A1
SCHEMBL8918250 0.75 PDE7A (0.31)
SCHEMBL8918900 0.70
SCHEMBL7831614 0.69 DAO (0.33) DAOALDH1A1
SCHEMBL8922231 0.69 KMT2A (0.33) PARP1PARP10PARP11ALDH1A1
SCHEMBL8920309 0.69 PARP1 (0.35) PARP1PARP10ALDH1A1
SCHEMBL7823082 0.66 DAO (0.31) DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed