SCHEMBL8920309

SCHEMBL8920309

Cc1ccc2c(c1)C(=N)NC21OCCO1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.35
PARP10 Q53GL7 1/20 0.35
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ROS1 P08922 1/20 0.32
CDK5 Q00535 1/20 0.32
ACVR1 Q04771 1/20 0.32
LRRK2 Q5S007 1/20 0.32
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8922231 0.87 KMT2A (0.33) PARP1PARP10KDM4EALDH1A1PDK2
SCHEMBL8918847 0.81 PPOX (0.37) PARP1PARP10LRRK2PDK2
SCHEMBL8919281 0.77 ALDH1A1 (0.40) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL8921171 0.77 ALDH1A1 (0.38) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL7828713 0.71 KDM4E (0.35) PARP1PARP10KDM4EALDH1A1MAPT
SCHEMBL8920932 0.71 PDE7A (0.38) KDM4EALDH1A1MAPTHSD17B10LRRK2
SCHEMBL8922236 0.67
SCHEMBL7823710 0.67 KDM4E (0.32) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL7827790 0.67 CA1 (0.42) PARP1PARP10KDM4EALDH1A1MAPT
SCHEMBL8918850 0.65 MAOA (0.46) MAPTHPGDPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
CN-1114431-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS (JP) 1996-01-03 CN disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed