Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 16/20 | 0.57 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893761 | 0.90 | ALOX5 (0.59) | ALOX5CYSLTR2CYSLTR1ALOX5APGPBAR1 | |
| SCHEMBL8902007 | 0.82 | CYSLTR2 (0.52) | ALOX5CYSLTR2CYSLTR1ALOX5APGPBAR1 | |
| SCHEMBL8922598 | 0.82 | ALOX5 (0.46) | ALOX5CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL8922928 | 0.79 | ALOX5 (0.46) | ALOX5CYSLTR2CYSLTR1ALOX5APGPBAR1 | |
| SCHEMBL8892196 | 0.79 | CYSLTR2 (0.50) | ALOX5CYSLTR2CYSLTR1ALOX5APGPBAR1 | |
| SCHEMBL8902508 | 0.75 | ALOX5 (0.42) | ALOX5CYSLTR2CYSLTR1ALOX5APGPBAR1 | |
| SCHEMBL8892197 | 0.75 | ALOX5 (0.42) | ALOX5CYSLTR2CYSLTR1ALOX5APGPBAR1 | |
| SCHEMBL8922287 | 0.71 | CYSLTR2 (0.64) | ALOX5CYSLTR2CYSLTR1ALOX5APGPBAR1 | |
| SCHEMBL8925370 | 0.70 | CYSLTR2 (0.63) | ALOX5CYSLTR2CYSLTR1ALOX5APGPBAR1 | |
| SCHEMBL8922290 | 0.70 | ALOX5AP (0.53) | ALOX5CYSLTR2CYSLTR1ALOX5APGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691351-A | Bis-(Heteroarylmethoxyphenyl)cycloalkyl carboxylates as inhibitors of leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1997-11-25 | — | — | US | disclosed |