Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | OGT | O15294 | 1/20 | 0.44 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919197 | 0.95 | CRBN (0.47) | CRBNGRIN2BNR3C1PGRSLC6A4 | |
| Hydrochloric Acid SCHEMBL7470903 | 0.91 | HSD11B1 (0.47) | CRBNGRIN2BITGB3ITGA2BCHIA | |
| SCHEMBL7286684 | 0.91 | CRBN (0.50) | CRBNGRIN2BNR3C1PGRSLC6A4 | |
| SCHEMBL8920578 | 0.86 | PDE3B (0.49) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| Oxalic Acid SCHEMBL8919236 | 0.86 | MEN1 (0.41) | CRBNGRIN2BMAOAMAOBOGT | |
| Hydrochloric Acid SCHEMBL7294149 | 0.86 | PDE3B (0.48) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL8919117 | 0.86 | CRBN (0.46) | CRBNGRIN2BNR3C1PGRSLC6A4 | |
| SCHEMBL8919777 | 0.85 | CHIA (0.42) | GRIN2BITGB3ITGA2BCHIAALDH1A1 | |
| Hydrochloric Acid SCHEMBL8919035 | 0.85 | GRIN2B (0.39) | GRIN2BITGB3ITGA2BCHIAALDH1A1 | |
| SCHEMBL7287837 | 0.84 | CRBN (0.49) | CRBNGRIN2BNR3C1PGRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591751-A | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0636128-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |
| WO-1994019339-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |