SCHEMBL16215324

SCHEMBL16215324

C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)CCCCCCCCCCc1ccc(-c2ccc(-c3ccc(C#N)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
HSD17B10 Q99714 1/20 0.56
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
FAAH O00519 1/20 0.37
HRH3 Q9Y5N1 4/20 0.35
MMP12 P39900 1/20 0.35
MMP13 P45452 1/20 0.35
CYP2A6 P11509 1/20 0.35
CYP19A1 P11511 4/20 0.34
ABCB1 P08183 1/20 0.34
HPGD P15428 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.34
KCNJ1 P48048 1/20 0.33
KCNH2 Q12809 1/20 0.33
LOXL2 Q9Y4K0 1/20 0.33
LSS P48449 1/20 0.33
KIF11 P52732 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8913600 0.81 RARB (0.48) TSHRHSD17B10MAPTFAAHABCB1
SCHEMBL17225143 0.81 TSHR (0.42) TSHRHSD17B10HRH3CYP2A6CYP19A1
SCHEMBL20646160 0.81 RAB9A (0.48) TSHRHSD17B10MAPTFAAHHPGD
SCHEMBL20646099 0.81 L3MBTL1 (0.52) TSHRHSD17B10MAPTFAAHHPGD
SCHEMBL9403378 0.81 TSHR (0.69) TSHRHSD17B10POLBMAPTFAAH
SCHEMBL20646094 0.79 TSHR (0.43) TSHRHSD17B10MAPTHRH3KCNJ1
SCHEMBL20646151 0.78 TSHR (0.41) TSHRHSD17B10MAPTFAAHHRH3
SCHEMBL20646153 0.78 HSD17B10 (0.41) TSHRHSD17B10POLBMAPTFAAH
SCHEMBL15045544 0.77 KDM4E (0.50) HRH3MMP13HPGD
SCHEMBL17225149 0.77 KDM4E (0.50) HRH3MMP13HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9175220-B2 High scattering smectic liquid crystal material and display device using the same HALATION PHOTONICS CORPORATION (CN) 2015-11-03 US disclosed
US-9175220-B2 High scattering smectic liquid crystal material and display device using the same HALATION PHOTONICS CORPORATION (CN) 2015-11-03 US disclosed
EP-2799516-A1 LIQUID CRYSTAL MATERIAL OF SMECTIC PHASE IN HIGH SCATTERING STATE AND DISPLAY DEVICE THEREOF Halation Photonics Corporation (CN) 2014-11-05 EP disclosed