Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 19/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 18/20 | 0.52 |
| ▸ | ITGB7 | P26010 | 10/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923071 | 1.00 | ITGA4 (0.52) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7411137 | 0.91 | ITGA4 (0.42) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7411125 | 0.91 | ITGA4 (0.42) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7413316 | 0.89 | MME (0.46) | — | |
| SCHEMBL7413308 | 0.89 | MME (0.46) | — | |
| SCHEMBL8921641 | 0.83 | MME (0.45) | — | |
| SCHEMBL8921663 | 0.83 | MME (0.45) | — | |
| SCHEMBL8923722 | 0.82 | PDCD1 (0.40) | — | |
| SCHEMBL8923760 | 0.82 | PDCD1 (0.40) | — | |
| SCHEMBL7415830 | 0.81 | ITGA4 (0.55) | ITGA4ITGB1ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660840-B1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | disclosed |
| US-5550119-A | ENDOTHELIN-CONVERTING ENZYM INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0660840-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES. | CIBA GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994005677-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1994-03-17 | — | — | WO | disclosed |