Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690173 | 1.00 | HTR2A (0.38) | HTR2AALDH1A1MAPTHPGDOPRK1 | |
| SCHEMBL8690188 | 0.89 | HTR2A (0.37) | HTR2AALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL8922847 | 0.89 | HTR2A (0.37) | HTR2AALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL9519619 | 0.86 | TDP1 (0.39) | HTR2AALDH1A1MAPTHPGDOPRK1 | |
| SCHEMBL9202417 | 0.84 | ALDH1A1 (0.35) | HTR2AALDH1A1MAPTHPGDOPRK1 | |
| SCHEMBL8693559 | 0.84 | ALDH1A1 (0.35) | HTR2AALDH1A1MAPTHPGDOPRK1 | |
| SCHEMBL9640607 | 0.83 | ALDH1A1 (0.42) | HTR2AALDH1A1MAPTHPGDOPRK1 | |
| SCHEMBL10739299 | 0.83 | ALDH1A1 (0.42) | HTR2AALDH1A1MAPTHPGDOPRK1 | |
| SCHEMBL8690166 | 0.83 | ALDH1A1 (0.38) | HTR2AALDH1A1MAPTHPGDOPRK1 | |
| SCHEMBL8923130 | 0.83 | ALDH1A1 (0.38) | HTR2AALDH1A1MAPTHPGDOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641770-A | THIENAMYCINS ANTIBIOTICS | CHONG KUN DANG CORP. (KR) | 1997-06-24 | — | — | US | disclosed |
| EP-0674640-A1 | 2-(2-SUBSTITUTED PYRROLIDIN-4-YL)THIO-CARBAPENEM DERIVATIVES | CHONG KUN DANG CORP (KR) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014811-A1 | 2-(2-SUBSTITUTED PYRROLIDIN-4-YL)THIO-CARBAPENEM DERIVATIVES | CHONG KUN DANG CORP. (KR) | 1994-07-07 | — | — | WO | disclosed |