Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694786 | 1.00 | ALDH1A1 (0.35) | ALDH1A1MAPTHPGDDPP4FAP | |
| SCHEMBL8694737 | 0.93 | ALDH1A1 (0.35) | ALDH1A1MAPTHPGDDPP4FAP | |
| SCHEMBL8690723 | 0.92 | ALDH1A1 (0.36) | ALDH1A1MAPTHPGDDPP4FAP | |
| SCHEMBL8689886 | 0.89 | ALDH1A1 (0.35) | ALDH1A1MAPTHPGDDPP4FAP | |
| SCHEMBL8924025 | 0.89 | ALDH1A1 (0.35) | ALDH1A1MAPTHPGDDPP4FAP | |
| SCHEMBL8692909 | 0.89 | DPP4 (0.34) | ALDH1A1MAPTHPGDDPP4FAP | |
| SCHEMBL8925688 | 0.89 | DPP4 (0.34) | ALDH1A1MAPTHPGDDPP4FAP | |
| SCHEMBL9388492 | 0.88 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDCCR5TDP1 | |
| SCHEMBL8690847 | 0.88 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDCCR5TDP1 | |
| SCHEMBL8924545 | 0.86 | CCR5 (0.34) | ALDH1A1MAPTHPGDDPP4FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641770-A | THIENAMYCINS ANTIBIOTICS | CHONG KUN DANG CORP. (KR) | 1997-06-24 | — | — | US | disclosed |
| WO-1994014811-A1 | 2-(2-SUBSTITUTED PYRROLIDIN-4-YL)THIO-CARBAPENEM DERIVATIVES | CHONG KUN DANG CORP. (KR) | 1994-07-07 | — | — | WO | disclosed |