SCHEMBL8923185

SCHEMBL8923185

O=Cc1cnc(N=NNc2ccc(Cl)cc2)s1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.33
ALDH1A1 P00352 5/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
TDP1 Q9NUW8 3/20 0.33
GAA P10253 2/20 0.33
LMNA P02545 1/20 0.33
GFER P55789 1/20 0.33
MEN1 O00255 2/20 0.33
RAB9A P51151 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
ALOX12 P18054 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
KCNJ1 P48048 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8991872 0.86 TDP1 (0.42) MAPTALDH1A1SMN1; SMN2TDP1GAA
SCHEMBL850770 0.66 SMN1; SMN2 (0.51) MAPTALDH1A1SMN1; SMN2GAALMNA
SCHEMBL11485490 0.65
SCHEMBL11485493 0.65
SCHEMBL24133218 0.64 CYP1B1 (0.63) MAPTALDH1A1SMN1; SMN2TDP1GAA
SCHEMBL8743004 0.64 MEN1 (0.56) MAPTALDH1A1SMN1; SMN2TDP1GAA
SCHEMBL8991869 0.63 NPC1 (0.47) MAPTALDH1A1TDP1GAARAB9A
SCHEMBL9387435 0.63 SMN1; SMN2 (0.41) SMN1; SMN2HTTNPSR1L3MBTL1
SCHEMBL2106305 0.62 STAT3 (0.60) MAPTALDH1A1SMN1; SMN2GFERMEN1
SCHEMBL360323 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0453020-B1 Black colored thermal dye sublimation transfer donor element AGFA GEVAERT NV (BE) 1995-01-18 EP claimed
JP-4226393-A None JP disclosed
US-5616697-A THIAZOLYL RING CONTAINS A SUBSTITUENT SELECTED FORM HYDROXY, ALKOXY, CYCLOALKOXY, ARYLOXY, MERCAPTO, THIOALKYL, THIOCYCLOALKYL AND THIOARYL AT 4-POSITION AGFA-GEVAERT, N.V. (BE) 1997-04-01 US disclosed
US-5169828-A Support with dye layer containing mixture of yellow dye and another dye; uniform high density images AGFA-GEVAERT, N.V. (BE) 1992-12-08 US disclosed
JP-H04226393-A BLACK COLORED THERMAL DYE SUBLIMATION TRANSFER DONOR MATERIAL AGFA GEVAERT NV 1992-08-17 JP disclosed