Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | IDE | P14735 | 1/20 | 0.54 |
| ▸ | MPI | P34949 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 3/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923373 | 0.87 | KDM4E (0.74) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8920123 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8922218 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8923424 | 0.83 | KDM4E (0.69) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8921296 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8920782 | 0.78 | KDM4E (0.73) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8922056 | 0.76 | GRIN1 (0.50) | KDM4EALDH1A1MAPTDAOGRIN2D | |
| SCHEMBL5313245 | 0.74 | ALDH1A1 (1.00) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8920155 | 0.72 | KDM4E (0.54) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17179367 | 0.72 | MAPT (1.00) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |