Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308388 | 0.95 | NPC1 (0.53) | NPC1RAB9ACYP2C9CYP2C19MAPT | |
| SCHEMBL28643879 | 0.84 | NPC1 (0.49) | NPC1RAB9ACYP2C9CYP2C19MAPT | |
| SCHEMBL96065 | 0.84 | KMT2A (0.50) | NPC1RAB9ACYP2C9CYP2C19MAPT | |
| SCHEMBL30463062 | 0.84 | KMT2A (0.50) | NPC1RAB9ACYP2C9CYP2C19MAPT | |
| SCHEMBL2559807 | 0.81 | MEN1 (0.43) | NPC1RAB9ACYP2C9CYP2C19MAPT | |
| SCHEMBL28882990 | 0.81 | TDP1 (0.39) | NPC1RAB9ACYP2C9CYP2C19MAPT | |
| SCHEMBL28883009 | 0.81 | MEN1 (0.44) | NPC1RAB9ACYP2C9CYP2C19MAPT | |
| SCHEMBL6834346 | 0.80 | AKR1C3 (0.49) | NPC1RAB9AMAPTGAAMEN1 | |
| SCHEMBL1713014 | 0.80 | MAPT (0.72) | NPC1RAB9ACYP2C9CYP2C19MAPT | |
| SCHEMBL4333864 | 0.80 | LMNA (0.60) | CYP2C9CYP2C19TDP1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10092786-B2 | Fire extinguishing composition comprising aldoketones compound | XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) | 2018-10-09 | — | — | US | claimed |
| US-20160332016-A1 | Fire Extinguishing Composition Comprising Aldoketones Compound | NANO FIRE, LLC | 2016-11-17 | — | — | US | claimed |
| US-10092786-B2 | Fire extinguishing composition comprising aldoketones compound | XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) | 2018-10-09 | — | — | US | disclosed |
| EP-3095487-A1 | FIRE EXTINGUISHING COMPOSITION COMPRISING ALDOKETONES COMPOUND | Xi'an J&R Fire Fighting Equipment Co., Ltd. (CN) | 2016-11-23 | — | — | EP | disclosed |
| US-20160332016-A1 | Fire Extinguishing Composition Comprising Aldoketones Compound | NANO FIRE, LLC | 2016-11-17 | — | — | US | disclosed |
| US-5631374-A | Reagents for detection of primary amines | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-05-20 | — | — | US | disclosed |
| US-5459272-A | Quinoline-2-(carboxaldehyde) reagents for detection of primary amines | RESEARCH CORPORATION TECHNOLOGIES (US) | 1995-10-17 | — | — | US | disclosed |
| WO-1992006961-A1 | 2-CARBOXALDEHYDE SUBSTITUTED QUINOLINE REAGENTS FOR THE DETECTION OF PRIMARY AMINO GROUPS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-04-30 | — | — | WO | disclosed |