SCHEMBL4333864

SCHEMBL4333864

O=Cc1ccccc1Nc1ccccc1C=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.60
KMT2A Q03164 2/20 0.60
MEN1 O00255 1/20 0.60
THRB P10828 1/20 0.60
BLM P54132 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
ALDH1A1 P00352 5/20 0.48
TRIM24 O15164 2/20 0.48
TRIM33 Q9UPN9 2/20 0.48
TSHR P16473 1/20 0.48
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
HPGD P15428 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GAA P10253 1/20 0.40
ERN1 O75460 2/20 0.39
CYP2A6 P11509 3/20 0.38
SRC P12931 1/20 0.38
ELANE P08246 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10984047 0.87 TRIM24 (0.59) LMNAKMT2AMEN1THRBBLM
SCHEMBL2558800 0.87 MEN1 (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL28859337 0.87 LMNA (0.46) LMNAKMT2AMEN1THRBBLM
SCHEMBL10695412 0.87 ALDH1A1 (0.59) LMNAKMT2AMEN1THRBBLM
SCHEMBL7357810 0.87 ERN1 (0.47) LMNAKMT2AMEN1THRBBLM
SCHEMBL11754542 0.87 MAPT (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL30463062 0.86 KMT2A (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL96065 0.86 KMT2A (0.50) LMNAKMT2AMEN1THRBBLM
SCHEMBL14306858 0.85 ALDH1A1 (0.47) LMNAKMT2AMEN1THRBBLM
SCHEMBL14306857 0.82 ALDH1A1 (0.42) LMNAKMT2AMEN1THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2050769-B1 Olefin polymerization catalyst and process for olefin polymerization MITSUI CHEMICALS INC (JP) 2013-05-22 EP disclosed
EP-2050769-A2 Olefin polymerization catalyst and process for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2009-04-22 EP disclosed
EP-0990664-B1 CATALYST FOR OLEFIN POLYMERIZATION AND METHOD OF POLYMERIZING OLEFIN MITSUI CHEMICALS INC (JP) 2009-03-11 EP disclosed
US-6399724-B1 FOR ALPHA-OLEFINS MITSUI CHEMICALS, INC. (JP) 2002-06-04 US disclosed
EP-0990664-A1 CATALYST FOR OLEFIN POLYMERIZATION AND METHOD OF POLYMERIZING OLEFIN Mitsui Chemicals, Inc. (JP) 2000-04-05 EP disclosed
EP-0453395-B1 Pressure sensitive recording material CIBA GEIGY AG (CH) 1995-11-02 EP disclosed
US-5254522-A Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1993-10-19 US disclosed
EP-0453395-A1 Pressure sensitive recording material CIBA-GEIGY AG (CH) 1991-10-23 EP disclosed