Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.70 |
| ▸ | PPARG | P37231 | 6/20 | 0.70 |
| ▸ | PPARD | Q03181 | 2/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768663 | 0.91 | PPARA (0.69) | PPARAPPARGPPARDHDAC6HDAC1 | |
| SCHEMBL8768761 | 0.89 | PPARA (0.57) | PPARAPPARGPPARDHDAC6HDAC1 | |
| SCHEMBL8768112 | 0.87 | PPARA (0.56) | PPARAPPARGPPARDHDAC6HDAC1 | |
| SCHEMBL8767784 | 0.86 | PPARA (0.61) | PPARAPPARGPPARDHDAC6HDAC1 | |
| SCHEMBL8768686 | 0.86 | PPARA (0.61) | PPARAPPARGPPARDHDAC6HDAC1 | |
| SCHEMBL8767727 | 0.86 | PPARA (0.61) | PPARAPPARGPPARDHDAC6HDAC1 | |
| SCHEMBL8767679 | 0.85 | PPARA (0.59) | PPARAPPARGPPARDHDAC6HDAC1 | |
| SCHEMBL8767753 | 0.82 | PPARA (0.62) | PPARAPPARGPPARDHDAC6HDAC1 | |
| SCHEMBL3967402 | 0.82 | PPARA (1.00) | PPARAPPARGPPARDSOAT1 | |
| SCHEMBL10891080 | 0.82 | HDAC6 (0.63) | HDAC6HDAC1HDAC3HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |