Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767684 | 0.85 | HDAC1 (0.49) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL8923396 | 0.82 | HDAC6 (0.47) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL9435378 | 0.81 | CNR1 (0.56) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL8768767 | 0.80 | PPARA (0.47) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL8923385 | 0.79 | PPARA (0.70) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL10891080 | 0.79 | HDAC6 (0.63) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL8768761 | 0.77 | PPARA (0.57) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL23584079 | 0.76 | HDAC1 (0.77) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL13911251 | 0.74 | ALDH1A1 (0.58) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL10891283 | 0.73 | HDAC6 (0.64) | HDAC6HDAC1HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |