Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921856 | 0.82 | POLB (0.41) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL8922395 | 0.81 | CYP4A11 (0.47) | MEN1KMT2AGAAALDH1A1ALOX15 | |
| SCHEMBL8923389 | 0.80 | ALDH1A1 (0.43) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL8921268 | 0.80 | CYP4F2 (0.52) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL8921195 | 0.78 | MAPT (0.48) | MEN1KMT2AGAAALDH1A1L3MBTL1 | |
| SCHEMBL8921377 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL6331207 | 0.70 | SMN1; SMN2 (0.62) | ALDH1A1TSHRL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL8921612 | 0.69 | SMN1; SMN2 (0.37) | KMT2AALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL8922762 | 0.69 | MALT1 (0.48) | TSHRLMNAPOLBHTTMAPT | |
| SCHEMBL11792109 | 0.69 | SMN1; SMN2 (0.61) | ALDH1A1TSHRL3MBTL1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| EP-0685466-A1 | 3-Heteroaliphatyle-and 3-hetero-(aryle)-aliphatyle-2(1H)-quinolone derivatives | CIBA-GEIGY AG (CH) | 1995-12-06 | — | — | EP | disclosed |