Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922106 | 0.85 | MCHR1 (0.35) | POLBMAPTMTNR1ATP53 | |
| SCHEMBL8922729 | 0.82 | MALT1 (0.49) | MALT1ACLYLMNAPOLBMAPT | |
| SCHEMBL8922733 | 0.80 | LMNA (0.42) | MALT1ACLYLMNAPOLBMAPT | |
| SCHEMBL8921928 | 0.72 | ALDH1A1 (0.45) | LMNAPOLBMAPTHTTTSHR | |
| SCHEMBL8921195 | 0.72 | MAPT (0.48) | ACLYMAPTHTT | |
| SCHEMBL8921377 | 0.72 | ALDH1A1 (0.46) | LMNAMAPT | |
| SCHEMBL8923394 | 0.69 | MEN1 (0.41) | LMNAPOLBMAPTHTTTSHR | |
| SCHEMBL8922100 | 0.68 | KMT2A (0.38) | LMNAPOLBMAPTMTNR1A | |
| SCHEMBL8922095 | 0.67 | MAPT (0.35) | LMNAPOLBMAPTMTNR1ATP53 | |
| SCHEMBL8922395 | 0.67 | CYP4A11 (0.47) | ACLYLMNAMAPTHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |