SCHEMBL8923522

SCHEMBL8923522

C=CC(=O)On1nnc2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SIRT2 Q8IXJ6 4/20 0.55
▸ HDAC3 O15379 3/20 0.53
▸ HDAC4 P56524 3/20 0.53
▸ HDAC1 Q13547 3/20 0.53
▸ HDAC7 Q8WUI4 3/20 0.53
▸ HDAC2 Q92769 3/20 0.53
▸ HDAC10 Q969S8 3/20 0.53
▸ HDAC11 Q96DB2 3/20 0.53
▸ HDAC8 Q9BY41 3/20 0.53
▸ HDAC6 Q9UBN7 3/20 0.53
▸ HDAC9 Q9UKV0 3/20 0.53
▸ HDAC5 Q9UQL6 3/20 0.53
▸ TSHR P16473 1/20 0.46
▸ NPSR1 Q6W5P4 1/20 0.46
▸ RXFP1 Q9HBX9 1/20 0.46
▸ SIRT1 Q96EB6 1/20 0.44
▸ SIRT3 Q9NTG7 1/20 0.44
▸ NPC1 O15118 2/20 0.44
▸ RAB9A P51151 2/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11197146 0.82 SIRT2 (0.52) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL39113 0.82 SIRT2 (0.61) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL1562975 0.82 SIRT2 (0.61) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL29773981 0.82 SIRT2 (0.61) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL239516 0.80 SIRT2 (0.60) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL30140830 0.80 SIRT2 (0.60) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL26598951 0.80 SIRT2 (0.60) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL28335039 0.80 KCNMA1 (0.43) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL2458394 0.79 SIRT2 (0.58) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL20445470 0.79 SIRT2 (0.58) SIRT2HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4549472-A2 COMPOSITIONS FOR SUNSCREEN COMPOUNDS AND METHODS THEREOF PMIDG, LLC (US) 2025-05-07 — — EP disclosed
EP-4013374-B1 COMPOSITIONS FOR SUNSCREEN COMPOUNDS AND METHODS THEREOF PMIDG LLC (US) 2025-02-19 — — EP disclosed
CN-118948676-A Compositions for sunscreen compounds and methods thereof 普米戴格有限公司 2024-11-15 — — CN disclosed
CN-118593387-A Compositions for sunscreen compounds and methods thereof 普米戴格有限公司 2024-09-06 — — CN disclosed
US-20220296485-A1 COMPOSITIONS FOR SUNSCREEN COMPOUNDS AND METHODS THEREOF PMIDG, LLC 2022-09-22 — — US disclosed
EP-4013374-A1 COMPOSITIONS FOR SUNSCREEN COMPOUNDS AND METHODS THEREOF PMIDG, LLC (US) 2022-06-22 — — EP disclosed
CN-114555038-A Compositions and methods for sunscreen compounds 普米戴格有限公司 2022-05-27 — — CN disclosed
WO-2021034834-A1 COMPOSITIONS FOR SUNSCREEN COMPOUNDS AND METHODS THEREOF PMIDG, LLC (US) 2021-02-25 — — WO disclosed
CN-107674079-B Synthesis method of ibrutinib 黑龙江珍宝岛药业股份有限公司 2019-12-13 — — CN disclosed
US-7635181-B2 Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same FUJIFILM CORPORATION (JP) 2009-12-22 — — US disclosed
US-7635181-B2 Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same FUJIFILM CORPORATION (JP) 2009-12-22 — — US disclosed
EP-1589374-B1 Polymerizable composition and process for producing lithographic plate using the polymerizable composition FUJIFILM CORP (JP) 2008-10-01 — — EP disclosed
US-7306894-B2 Polymerizable composition, photopolymerizing method and process for producing lithographic printing plate using the polymerizable composition FUJIFILM CORPORATION (JP) 2007-12-11 — — US disclosed
US-7306894-B2 Polymerizable composition, photopolymerizing method and process for producing lithographic printing plate using the polymerizable composition FUJIFILM CORPORATION (JP) 2007-12-11 — — US disclosed
CN-1047779-C Anti-tanning agent, and light-protection cosmetic composition containing said agent and application thereof OREAL (FR) 1999-12-29 — — CN disclosed
US-5629365-A POLYMERS OF VINYL SUBSTITUTED BENZOTRIAZOLES AND BENZOPHENONES DISPERSED IN LATEX, PROTECTIVE COATINGS AND FILMS MONSANTO COMPANY (US) 1997-05-13 — — US disclosed
CN-1135487-A Anti-tanning agent, and light-protection cosmetic composition containing said agent and application thereof OREAL (FR) 1996-11-13 — — CN disclosed
EP-0361229-B1 Polymer-bonded dyes, process for their preparation and their use BAYER AG (DE) 1994-04-27 — — EP disclosed
EP-0361229-A2 Polymer-bonded dyes, process for their preparation and their use BAYER AG (DE) 1990-04-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220296485-A1 COMPOSITIONS FOR SUNSCREEN COMPOUNDS AND METHODS THEREOF NQO1, XPA, ERCC1 SIRT2 270/4885HDAC3 3764/4885HDAC4 2864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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