SCHEMBL892355

SCHEMBL892355

C=C(C)C(=O)OC.CC(=CC=C(C)C(=O)O)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
TSHR P16473 3/20 0.38
PTGS1 P23219 1/20 0.38
THRB P10828 1/20 0.31
APEX1 P27695 2/20 0.31
EGLN1 Q9GZT9 1/20 0.30
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8161723 0.87 ALDH1A1 (0.65) ALDH1A1TSHRTHRBAPEX1EGLN1
SCHEMBL9329248 0.87 ALDH1A1 (0.65) ALDH1A1TSHRTHRBAPEX1EGLN1
SCHEMBL9500702 0.86 ALDH1A1 (0.48) ALDH1A1TSHRPTGS1THRB
Methacrylic Acid SCHEMBL30076053 0.85 ALDH1A1 (0.62) ALDH1A1TSHRTHRBAPEX1
SCHEMBL2726802 0.84 PTGS1 (0.41) ALDH1A1PTGS1APEX1EGLN1
Methacrylic Acid SCHEMBL8375014 0.84 ALDH1A1 (0.83) ALDH1A1TSHRTHRBEGLN1ELANE
Methacrylic Acid SCHEMBL10493520 0.84 ALDH1A1 (0.83) ALDH1A1TSHRTHRBEGLN1ELANE
Methacrylic Acid SCHEMBL121002 0.84 ALDH1A1 (0.83) ALDH1A1TSHRTHRBEGLN1ELANE
Methacrylic Acid SCHEMBL1171642 0.84 ALDH1A1 (0.83) ALDH1A1TSHRTHRBEGLN1ELANE
Methacrylic Acid SCHEMBL28927748 0.84 ALDH1A1 (0.83) ALDH1A1TSHRTHRBEGLN1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9205130-B2 Orally administrable pharmaceutical pellet of epidermal growth factor CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) 2015-12-08 US claimed
US-20120308661-A1 ORALLY ADMINISTRABLE PHARMACEUTICAL PELLET OF EPIDERMAL GROWTH FACTOR BIOREC S. A. (UY) 2012-12-06 US claimed
US-20200179288-A1 Omeprazole Formulations SANDOZ AG (CH) 2020-06-11 US disclosed
EP-3380084-B1 OMEPRAZOLE FORMULATIONS SANDOZ AG (CH) 2019-08-21 EP disclosed
EP-3380084-A1 OMEPRAZOLE FORMULATIONS Sandoz AG (CH) 2018-10-03 EP disclosed
WO-2018046498-A1 OMEPRAZOLE FORMULATIONS SANDOZ AG (CH) 2018-03-15 WO disclosed
EP-3292862-A1 OMEPRAZOLE FORMULATIONS SANDOZ AG (CH) 2018-03-14 EP disclosed
EP-2604256-B1 Multi layer coatings HEXAL AG (DE) 2016-04-13 EP disclosed
US-9205130-B2 Orally administrable pharmaceutical pellet of epidermal growth factor CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) 2015-12-08 US disclosed
EP-2604256-A1 Multi layer coatings Hexal AG (DE) 2013-06-19 EP disclosed
US-20120308661-A1 ORALLY ADMINISTRABLE PHARMACEUTICAL PELLET OF EPIDERMAL GROWTH FACTOR BIOREC S. A. (UY) 2012-12-06 US disclosed
US-20120082721-A1 Enteric coating H E X A L AKTIENGESELLSCHAFT (DE) 2012-04-05 US disclosed
EP-2343054-A1 Pellets and microparticles of pravastatin sodium and a process of making them LEK Pharmaceuticals d.d. (SI) 2011-07-13 EP disclosed
WO-2011080346-A2 PELLETS AND MICROPARTICLES OF PRAVASTATIN SODIUM AND A PROCESS OF MAKING THEM LEK PHARMACEUTICALS D.D. (SI) 2011-07-07 WO disclosed
WO-2010136219-A1 ENTERIC COATING HEXAL AKTIENGESELLSCHAFT (DE) 2010-12-02 WO disclosed
EP-2255794-A1 Enteric coating H e x a l Aktiengesellschaft (DE) 2010-12-01 EP disclosed