SCHEMBL2726802

SCHEMBL2726802

COC(=O)C(C)=CC=C(C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.41
ALDH1A1 P00352 4/20 0.40
APEX1 P27695 3/20 0.33
EGLN1 Q9GZT9 1/20 0.33
AKR1C3 P42330 1/20 0.32
HCAR2 Q8TDS4 2/20 0.32
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
ALOX15 P16050 1/20 0.31
RECQL P46063 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27485285 0.98 PTGS1 (0.40) PTGS1ALDH1A1APEX1EGLN1AKR1C3
SCHEMBL3723391 0.93 PTGS1 (0.38) PTGS1ALDH1A1APEX1EGLN1
SCHEMBL25246818 0.89 ALDH1A1 (0.48) ALDH1A1EGLN1HCAR2KEAP1NFE2L2
SCHEMBL8582233 0.89 PTGS1 (0.52) PTGS1ALDH1A1APEX1EGLN1ALOX15
SCHEMBL18070830 0.85 ALDH1A1 (0.40) ALDH1A1EGLN1HCAR2KEAP1NFE2L2
SCHEMBL892355 0.84 ALDH1A1 (0.65) PTGS1ALDH1A1APEX1EGLN1
SCHEMBL19526556 0.83 ALDH1A1 (0.39) ALDH1A1EGLN1HCAR2KEAP1NFE2L2
SCHEMBL11255718 0.82 ALDH1A1 (0.42) ALDH1A1EGLN1HCAR2KEAP1NFE2L2
SCHEMBL294152 0.82 ALDH1A1 (0.42) ALDH1A1EGLN1HCAR2KEAP1NFE2L2
SCHEMBL294153 0.82 ALDH1A1 (0.42) ALDH1A1EGLN1HCAR2KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3931609-A1 VARIABLE-ETCH-DEPTH GRATINGS Facebook Technologies, LLC. (US) 2022-01-05 EP claimed
US-10976483-B2 Variable-etch-depth gratings FACEBOOK TECHNOLOGIES, LLC (US) 2021-04-13 US claimed
US-20200271850-A1 VARIABLE-ETCH-DEPTH GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2020-08-27 US claimed
US-20160161475-A1 HYBRID SEMICONDUCTING POLYMER NANOPARTICLES AS POLARIZATION-SENSITIVE FLUORESCENT PROBES UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION 2016-06-09 US claimed
EP-3019443-A1 HYBRID SEMICONDUCTING POLYMER NANOPARTICLES AS POLARIZATION SENSITIVE FLUORESCENT PROBES University Of Washington Through Its Center For Commercialization (US) 2016-05-18 EP claimed
US-20160018405-A1 METHODS AND SYSTEMS FOR ANALYSIS USING POLYMER DOTS University of Washington Through it's Center for Commercialization (US) 2016-01-21 US claimed
EP-2964565-A1 WESTERN BLOT ANALYSIS USING POLYMER DOTS University Of Washington Through Its Center For Commercialization (US) 2016-01-13 EP claimed
CN-103357277-B A kind of have milipore filter of heavy metal ion adsorbed function and preparation method thereof ZHEJIANG NORMAL UNIVERSITY (CN) 2015-12-09 CN claimed
WO-2014138312-A1 WESTERN BLOT ANALYSIS USING POLYMER DOTS UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2014-09-12 WO claimed
CN-103357277-A Ultrafiltration membrane with heavy metal ion adsorption function, and preparation method thereof UNIV ZHEJIANG NORMAL 2013-10-23 CN claimed
CN-100463861-C Method of preparing ordered porous titanium oxide doped with nitrogen WUHAN INST TECHNOLOGY (CN) 2009-02-25 CN claimed
CN-101345112-A Magnetic inorganic hollow compound microsphere and preparation method thereof UNIV FUDAN (CN) 2009-01-14 CN claimed
CN-100370001-C High Tg polymer emulsion and blend of contact adhesive polymer emulsion for contact adhesive AIR PRODUCTS POLYMER INC (US) 2008-02-20 CN claimed
CN-101066525-A Process of preparing micron level ordered porous aza titania microsphere UNIV WUHAN ENGINEERING (CN) 2007-11-07 CN claimed
CN-101012069-A Method of preparing ordered porous titanium oxide doped with nitrogen WUHAN INST TECHNOLOGY (CN) 2007-08-08 CN claimed
EP-1617842-A1 ORAL PHARMACEUTICAL FORMULATIONS COMPRISING ACID-LABILE ACTIVE INGREDIENTS AND A WATER-SOLUBLE SUGAR DERIVATE, USE THEREOF AND THE SUITABLE PROCESS FOR MANUFACTURING THESE Dr. Reddy's Laboratories Ltd. (IN) 2006-01-25 EP claimed
US-20050031696-A1 Oral pharmaceutical formulations of acid-labile active ingredients and process for making same DR. REDDY'S LABORATORIES LIMITED 2005-02-10 US claimed
WO-2004093875-A1 ORAL PHARMACEUTICAL FORMULATIONS COMPRISING ACID-LABILE ACTIVE INGREDIENTS AND A WATER-SOLUBLE SUGAR DERIVATE, USE THEREOF AND THE SUITABLE PROCESS FOR MANUFACTURING THESE DR. REDDY'S LABORATORIES LIMITED (IN) 2004-11-04 WO claimed
CN-1537912-A Blends of high T.g polymer emulsions and pressure sensitive adhesive polymer emulsion usefuel as pressure sensitive adhesives �����Ʒ�ۺ��﹫˾ 2004-10-20 CN claimed
CN-1396229-A High Tg polymer emulsion and blend of contact adhesive polymer emulsion for contact adhesive AIR PRODUCTS POLYMER INC (US) 2003-02-12 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050031696-A1 Oral pharmaceutical formulations of acid-labile active ingredients and process for making same SI, GAA, PGA5 PTGS1 381/4885ALDH1A1 290/4885APEX1 2089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.