SCHEMBL892363

SCHEMBL892363

C#CCC(CCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HLCS P50747 6/20 0.60
TDP1 Q9NUW8 6/20 0.57
MEN1 O00255 1/20 0.57
ABL1 P00519 1/20 0.57
LMNA P02545 1/20 0.57
PKM P14618 1/20 0.57
IDE P14735 1/20 0.57
MAPK1 P28482 1/20 0.57
KMT2A Q03164 1/20 0.57
RIN1 Q13671 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
CA12 O43570 5/20 0.41
CA1 P00915 5/20 0.41
CA2 P00918 5/20 0.41
CA9 Q16790 5/20 0.41
FOLH1 Q04609 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL425273 0.89 TDP1 (0.67) HLCSTDP1MEN1ABL1LMNA
SCHEMBL31578494 0.85 HLCS (0.45) HLCSTDP1MEN1ABL1LMNA
SCHEMBL4740139 0.83 TDP1 (0.60) HLCSTDP1MEN1ABL1LMNA
SCHEMBL487045 0.82 TDP1 (0.68) HLCSTDP1MEN1ABL1LMNA
SCHEMBL4454446 0.82 TDP1 (0.58) HLCSTDP1MEN1ABL1LMNA
SCHEMBL1403829 0.82 TDP1 (0.77) HLCSTDP1MEN1ABL1LMNA
SCHEMBL4466074 0.82 HLCS (0.72) HLCSTDP1MEN1ABL1LMNA
SCHEMBL1527196 0.82 TDP1 (0.58) HLCSTDP1MEN1ABL1LMNA
SCHEMBL3839854 0.82 TDP1 (0.58) HLCSTDP1MEN1ABL1LMNA
SCHEMBL7122397 0.82 TDP1 (0.61) HLCSTDP1MEN1ABL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114578043-B ELISA kit, preparation method and detection method thereof 伊莱瑞特(武汉)生物技术有限公司 2024-08-20 CN claimed
CN-114578043-A ELISA kit and preparation method and detection method thereof 伊莱瑞特(武汉)生物技术有限公司 2022-06-03 CN claimed
CN-114578043-A ELISA kit and preparation method and detection method thereof 伊莱瑞特(武汉)生物技术有限公司 2022-06-03 CN disclosed
US-20120083599-A1 Biomolecular Labelling Using Multifunctional Biotin Analogues UNIVERSITY OF NOTTINGHAM (GB) 2012-04-05 US disclosed
US-20120083599-A1 Biomolecular Labelling Using Multifunctional Biotin Analogues UNIVERSITY OF NOTTINGHAM (GB) 2012-04-05 US disclosed
US-20120083599-A1 Biomolecular Labelling Using Multifunctional Biotin Analogues UNIVERSITY OF NOTTINGHAM (GB) 2012-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120083599-A1 Biomolecular Labelling Using Multifunctional Biotin Analogues BTD, URB2, RAET1L HLCS 7/4885TDP1 4767/4885MEN1 3602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.