Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MIF | P14174 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923628 | 1.00 | RXRA (0.60) | RXRAMAPTMIFCYP1A2CYP2D6 | |
| SCHEMBL12629637 | 1.00 | RXRA (0.60) | RXRAMAPTMIFCYP1A2CYP2D6 | |
| SCHEMBL3253387 | 0.96 | RXRA (0.60) | RXRAMAPTMIFCYP1A2CYP2D6 | |
| SCHEMBL9179498 | 0.89 | MAOB (0.50) | RXRAMIFCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3697186 | 0.89 | MAOB (0.50) | RXRAMIFCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3697185 | 0.89 | MAOB (0.50) | RXRAMIFCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL12808897 | 0.84 | RXRA (0.79) | RXRAMAPTMIFCYP19A1CYP11B1 | |
| SCHEMBL8780459 | 0.84 | RXRA (0.56) | RXRAMAPTMIFCYP19A1CYP11B1 | |
| SCHEMBL8780455 | 0.84 | RXRA (0.56) | RXRAMAPTMIFCYP19A1CYP11B1 | |
| SCHEMBL13545387 | 0.80 | RXRA (0.52) | RXRAMAPTMIFCYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2730918-B1 | MATRIX FOR MALDI MASS SPECTROMETRY AND MALDI MASS SPECTROMETRY METHOD | UNIV KYUSHU NAT UNIV CORP (JP) | 2016-09-14 | — | — | EP | disclosed |
| US-20140151548-A1 | MATRIX FOR MALDI MASS SPECTROMETRY AND MALDIMASS SPECTROMETRY METHOD | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-2730918-A1 | MATRIX FOR MALDI MASS SPECTROMETRY | Kyushu University National University Corporation (JP) | 2014-05-14 | — | — | EP | disclosed |
| EP-0802897-A1 | NOVEL COMPOUNDS | Smithkline Beecham S.p.A. (IT) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021638-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM S.P.A. (IT) | 1996-07-18 | — | — | WO | disclosed |