Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925726 | 1.00 | PSEN1 (0.44) | PSEN1PPARAPPARGMEN1KMT2A | |
| SCHEMBL8767474 | 0.85 | ALOX5 (0.51) | PPARAPPARGMEN1KMT2AMAPT | |
| SCHEMBL8767480 | 0.85 | ALOX5 (0.51) | PPARAPPARGMEN1KMT2AMAPT | |
| SCHEMBL8768724 | 0.82 | ALOX5 (0.49) | PPARAPPARGMEN1KMT2AMAPT | |
| SCHEMBL8768719 | 0.82 | ALOX5 (0.49) | PPARAPPARGMEN1KMT2AMAPT | |
| SCHEMBL8923653 | 0.81 | PSEN1 (0.38) | PSEN1PPARAPPARGMEN1KMT2A | |
| SCHEMBL8923656 | 0.81 | PSEN1 (0.38) | PSEN1PPARAPPARGMEN1KMT2A | |
| SCHEMBL8923654 | 0.81 | PSEN1 (0.38) | PSEN1PPARAPPARGMEN1KMT2A | |
| SCHEMBL8039151 | 0.74 | PSEN1 (0.42) | PSEN1PPARAMEN1KMT2APDE4A | |
| SCHEMBL9075355 | 0.73 | MEN1 (0.42) | PSEN1MEN1KMT2APDE4APDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627205-A | ANTILIPEMIC AGENTS AND ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 1997-05-06 | — | — | US | disclosed |