Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | AOC1 | P19801 | 3/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
| ▸ | GLP1R | P43220 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17372486 | 0.76 | AOC1 (0.57) | KAT2BAOC1AOC3MAPTNR4A2 | |
| SCHEMBL17372397 | 0.76 | RXFP1 (0.36) | KAT2BAOC1AOC3MAPTNR4A2 | |
| SCHEMBL4474079 | 0.76 | AOC1 (0.43) | KAT2BAOC1AOC3MAPT | |
| SCHEMBL8923850 | 0.76 | MAPT (0.50) | KAT2BAOC1AOC3MAPTGAA | |
| SCHEMBL18934401 | 0.73 | AOC1 (0.56) | KAT2BAOC1AOC3MAPTNR4A2 | |
| SCHEMBL5768195 | 0.73 | AOC1 (0.51) | KAT2BAOC1AOC3MAPTNR4A2 | |
| SCHEMBL8917595 | 0.69 | KAT2B (0.46) | KAT2BAOC1AOC3NR4A2GAA | |
| SCHEMBL8165575 | 0.68 | NR4A2 (0.47) | MAPTNR4A2 | |
| SCHEMBL337576 | 0.68 | — | — | |
| SCHEMBL22767491 | 0.67 | CYP1A2 (0.34) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599930-A | Substituted indoles as anti-AIDS pharmaceuticals | THE UPJOHN COMPANY (US) | 1997-02-04 | — | — | US | disclosed |