Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928009 | 0.80 | HTT (0.60) | LMNAKDM4EHTTSMN1; SMN2OPRK1 | |
| SCHEMBL9848406 | 0.77 | AKT1 (0.61) | LMNAKDM4EHTTSMN1; SMN2OPRK1 | |
| SCHEMBL10013666 | 0.76 | DPP4 (0.50) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL31644092 | 0.75 | S1PR3 (0.66) | LMNAKDM4EHTTSMN1; SMN2OPRK1 | |
| SCHEMBL4942910 | 0.73 | CTSA (0.60) | LMNAKDM4EHTTSMN1; SMN2OPRK1 | |
| SCHEMBL7377820 | 0.73 | SMN1; SMN2 (0.56) | LMNAKDM4EHTTSMN1; SMN2OPRK1 | |
| SCHEMBL15145589 | 0.73 | KDM4E (0.54) | LMNAKDM4EHTTSMN1; SMN2OPRK1 | |
| SCHEMBL1106971 | 0.73 | KDM4E (0.63) | LMNAKDM4EHTTSMN1; SMN2OPRK1 | |
| SCHEMBL19797800 | 0.73 | DPP4 (0.46) | LMNAKDM4EHDAC1HDAC6ALDH1A1 | |
| SCHEMBL7058262 | 0.72 | KDM4E (0.52) | LMNAKDM4EHTTSMN1; SMN2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602267-A | Organometallic catalysts for epoxidizing prochiral olefins and a new class of amid-salicylidene ligands | HOECHST CELANESE (US) | 1997-02-11 | — | — | US | disclosed |