Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928009 | 0.79 | HTT (0.60) | KDM4EHTTLMNAOPRK1SMN1; SMN2 | |
| SCHEMBL2029476 | 0.76 | MAPT (0.41) | HTTLMNASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL31644092 | 0.74 | S1PR3 (0.66) | KDM4EHTTLMNAOPRK1SMN1; SMN2 | |
| SCHEMBL27524142 | 0.73 | ALDH1A1 (0.50) | HTTLMNASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL6789222 | 0.73 | ACACB (0.57) | KDM4EHTTLMNAOPRK1TDP1 | |
| SCHEMBL6794110 | 0.73 | ACACB (0.57) | KDM4EHTTLMNAOPRK1TDP1 | |
| SCHEMBL27583336 | 0.73 | ACACB (0.57) | KDM4EHTTLMNAOPRK1TDP1 | |
| SCHEMBL11020298 | 0.73 | KDM4E (0.49) | KDM4EHTTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL8924030 | 0.72 | LMNA (0.54) | KDM4EHTTLMNAOPRK1SMN1; SMN2 | |
| SCHEMBL9848406 | 0.72 | AKT1 (0.61) | KDM4EHTTLMNAOPRK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003026664-A1 | 2-PHENYLAMINO-4- (5-PYRAZOLYLAMINO) -PYRAMIDINE DERIVATIVES AS KINASE INHIBITORS, IN PARTICULAR, SRC KINASE INHIBITORS | BAYER CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |