Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 6/20 | 0.61 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.61 |
| ▸ | GSK3B | P49841 | 2/20 | 0.61 |
| ▸ | NEK4 | P51957 | 2/20 | 0.61 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.61 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.61 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.61 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.61 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.61 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.61 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.61 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.61 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.61 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.61 |
| ▸ | PRKCG | P05129 | 1/20 | 0.61 |
| ▸ | CDK1 | P06493 | 1/20 | 0.61 |
| ▸ | PIM1 | P11309 | 1/20 | 0.61 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4942910 | 0.85 | CTSA (0.60) | EPHX2KDM4ELMNAOPRK1HTT | |
| SCHEMBL6188521 | 0.81 | TACR3 (0.53) | ROCK1ROCK2EPHX2KDM4ELMNA | |
| SCHEMBL8861463 | 0.81 | EPHX2 (0.50) | EPHX2KDM4ELMNAOPRK1HTT | |
| SCHEMBL28928009 | 0.80 | HTT (0.60) | EPHX2KDM4ELMNAOPRK1HTT | |
| SCHEMBL9848486 | 0.78 | RPS6KA5 (0.71) | AKT1RPS6KA5GSK3BNEK4PRKCD | |
| SCHEMBL14261926 | 0.77 | CTSA (0.64) | — | |
| SCHEMBL8924030 | 0.77 | LMNA (0.54) | EPHX2KDM4ELMNAOPRK1HTT | |
| SCHEMBL3105352 | 0.76 | ROCK2 (1.00) | AKT1RPS6KA5GSK3BNEK4PRKCD | |
| SCHEMBL3112038 | 0.76 | ROCK2 (1.00) | AKT1RPS6KA5GSK3BNEK4PRKCD | |
| SCHEMBL3109328 | 0.76 | ROCK2 (1.00) | AKT1RPS6KA5GSK3BNEK4PRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432442-A1 | ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |