Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | CBFB | Q13951 | 4/20 | 0.40 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | METAP1 | P53582 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757498 | 0.83 | KDM4E (0.49) | KDM4ENPC1CBFBMETAP2METAP1 | |
| SCHEMBL6757461 | 0.81 | ULK1 (0.48) | KDM4ENPC1GAACBFBMETAP2 | |
| SCHEMBL6762551 | 0.79 | KDM4E (0.51) | KDM4ENPC1CBFBMETAP2METAP1 | |
| SCHEMBL6761705 | 0.79 | TGFBR1 (0.44) | KDM4ENPC1CBFBMETAP2METAP1 | |
| SCHEMBL6762500 | 0.78 | GRM5 (0.49) | KDM4ENPC1CBFBMETAP2METAP1 | |
| SCHEMBL6764632 | 0.77 | NPC1 (0.41) | KDM4ENPC1CBFBMETAP2METAP1 | |
| SCHEMBL6759912 | 0.76 | KDM4E (0.40) | KDM4ENPC1CBFBMETAP2METAP1 | |
| SCHEMBL6759961 | 0.75 | BRAF (0.48) | ESR1ESR2KDM4ENPC1METAP2 | |
| SCHEMBL3851861 | 0.74 | KDM4E (0.55) | KDM4ENPC1METAP1GRM5PKM | |
| SCHEMBL29871087 | 0.74 | KDM4E (0.55) | KDM4ENPC1METAP1GRM5PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9124640-A | — | — | None | — | — | JP | disclosed |
| JP-H09124640-A | PYRIDYLIMIDAZOLE COMPOUND, PRODUCTION THEREOF AND FUNGICIDE FOR AGRICULTURAL AND HORTICULTURAL USE | NIPPON SODA CO LTD | 1997-05-13 | — | — | JP | disclosed |