Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | GALK1 | P51570 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 3/20 | 0.39 |
| ▸ | PYGM | P11217 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1100529 | 0.92 | POLB (0.51) | HPSEPOLBTDP1GALK1CASP6 | |
| SCHEMBL29779713 | 0.92 | POLB (0.51) | HPSEPOLBTDP1GALK1CASP6 | |
| SCHEMBL9852598 | 0.89 | HPSE (0.49) | HPSEPOLBTDP1GALK1CASP6 | |
| SCHEMBL8923122 | 0.87 | POLB (0.52) | HPSEPOLBTDP1GALK1CASP6 | |
| SCHEMBL9153473 | 0.83 | POLB (0.51) | HPSEPOLBTDP1GALK1CASP6 | |
| SCHEMBL28394217 | 0.83 | HPSE (0.48) | HPSEPOLBTDP1GALK1CASP6 | |
| SCHEMBL28885523 | 0.83 | HPSE (0.48) | HPSEPOLBTDP1GALK1CASP6 | |
| SCHEMBL29907832 | 0.80 | POLB (0.54) | HPSEPOLBTDP1GALK1CASP6 | |
| SCHEMBL1099667 | 0.80 | POLB (0.54) | HPSEPOLBTDP1GALK1CASP6 | |
| SCHEMBL8923161 | 0.79 | HSD17B10 (0.47) | TDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670084-A | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0708149-A1 | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-24 | — | — | EP | disclosed |