SCHEMBL8924130

SCHEMBL8924130

CCCCCCCCn1nnnc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 2/20 0.46
HTT P42858 1/20 0.43
CYP2C19 P33261 1/20 0.41
SLC9A1 P19634 2/20 0.40
POLB P06746 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9111798 1.00 HCAR3 (0.46) HCAR3HTTCYP2C19SLC9A1POLB
SCHEMBL28712647 0.86 HSD17B10 (0.43) HCAR3CYP2C19POLBHPGD
Silver SCHEMBL10952229 0.84 HTT (0.41) HCAR3HTTCYP2C19SLC9A1
SCHEMBL6581738 0.80 RARB (0.38) HTTCYP2C19
SCHEMBL9138151 0.79 HCAR3 (0.36) HCAR3HTTCYP2C19
SCHEMBL9138156 0.79 HCAR3 (0.36) HCAR3HTTCYP2C19
SCHEMBL6948864 0.78 NPC1 (0.48) HCAR3CYP2C19POLB
SCHEMBL28711301 0.78 HCAR3 (0.41) HCAR3HTTCYP2C19SLC9A1POLB
SCHEMBL28703270 0.78 HCAR3 (0.41) HCAR3HTTCYP2C19SLC9A1POLB
SCHEMBL28711340 0.78 HCAR3 (0.41) HCAR3HTTCYP2C19SLC9A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5597929-A Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran SUMITOMO CHEMICAL CO., LTD. (JP) 1997-01-28 US disclosed
EP-0716088-A1 PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-12 EP disclosed