Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138156 | 1.00 | HCAR3 (0.36) | HCAR3HTTCYP2C19 | |
| SCHEMBL8924130 | 0.79 | HCAR3 (0.46) | HCAR3HTTCYP2C19 | |
| SCHEMBL9111798 | 0.79 | HCAR3 (0.46) | HCAR3HTTCYP2C19 | |
| SCHEMBL9138211 | 0.74 | TRPV1 (0.40) | — | |
| SCHEMBL9138218 | 0.74 | TRPV1 (0.40) | — | |
| Silver SCHEMBL10952229 | 0.74 | HTT (0.41) | HCAR3HTTCYP2C19 | |
| SCHEMBL28711340 | 0.68 | HCAR3 (0.41) | HCAR3HTTCYP2C19 | |
| SCHEMBL28704641 | 0.68 | HCAR3 (0.41) | HCAR3HTTCYP2C19 | |
| SCHEMBL28702017 | 0.68 | HCAR3 (0.41) | HCAR3HTTCYP2C19 | |
| SCHEMBL28702006 | 0.68 | HCAR3 (0.41) | HCAR3HTTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995032953-A1 | AMIDE TETRAZOLE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1995-12-07 | — | — | WO | disclosed |
| US-5461049-A | Treating hypercholesterolemia, atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1995-10-24 | — | — | US | disclosed |