SCHEMBL8924189

SCHEMBL8924189

FC(Cl)=C(F)C(F)(F)C(F)F

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9461133 1.00 PKM (0.34) PKM
SCHEMBL22501869 0.81 PKM (0.34) PKM
SCHEMBL22028660 0.80
SCHEMBL20548192 0.80 PKM (0.31) PKM
SCHEMBL20548190 0.80 PKM (0.31) PKM
SCHEMBL251040 0.78 PKM (0.36) PKM
SCHEMBL2322986 0.75 PKM (0.34) PKM
SCHEMBL7632280 0.75 PKM (0.34) PKM
SCHEMBL9721358 0.75 PKM (0.34) PKM
SCHEMBL333516 0.75 PKM (0.34) PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4692032-A2 SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244BB DEHYDROCHLORINATION TO 1234YF Honeywell International Inc. (US) 2026-02-11 EP claimed
EP-3737660-B1 SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244BB DEHYDROCHLORINATION TO 1234YF HONEYWELL INT INC (US) 2025-11-05 EP claimed
CN-117986080-A System and method for reducing impurity formation during dehydrochlorination of 244bb to 1234yf 霍尼韦尔国际公司 2024-05-07 CN claimed
CN-117986081-A System and method for reducing impurity formation during dehydrochlorination of 244bb to 1234yf 霍尼韦尔国际公司 2024-05-07 CN claimed
EP-3737659-A1 COMPOSITIONS CONTAINING 2-CHLORO-1,1,1,2-TETRAFLUOROPROPANE (HCFC-244BB) Honeywell International Inc. (US) 2020-11-18 EP claimed
EP-3737660-A1 SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244BB DEHYDROCHLORINATION TO 1234YF Honeywell International Inc. (US) 2020-11-18 EP claimed
CN-108741412-B Decompression antifatigue shoe-pad of taking a step 东莞市顺风运动器材有限公司 2020-11-13 CN claimed
CN-111699167-A Compositions comprising 2-chloro-1, 1,1, 2-tetrafluoropropane (HCFC-244bb) 霍尼韦尔国际公司 2020-09-22 CN claimed
CN-111699168-A Systems and methods for reducing impurity formation during dehydrochlorination of 244bb to 1234yf 霍尼韦尔国际公司 2020-09-22 CN claimed
WO-2019136408-A1 COMPOSITIONS CONTAINING 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) HONEYWELL INTERNATIONAL INC. (US) 2019-07-11 WO claimed
US-20190210945-A1 COMPOSITIONS CONTAINING 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) SOLSTICE ADVANCED MATERIALS US, INC. 2019-07-11 US claimed
WO-2019136410-A1 SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244bb DEHYDROCHLORINATION TO 1234yf HONEYWELL INTERNATIONAL INC. (US) 2019-07-11 WO claimed
US-10246389-B1 Compositions containing 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) HONEYWELL INTERNATIONAL INC. (US) 2019-04-02 US claimed
EP-0639169-B1 PROCESS FOR PRODUCING HEXAFLUOROCHLOROBUTENES BAYER AG (DE) 1997-01-08 EP claimed
US-5523497-A Process for preparing hexafluorochlorobutenes BAYER AKTIENGESELLSCHAFT (DE) 1996-06-04 US claimed
JP-5279274-A None JP disclosed
JP-5194285-A None JP disclosed
US-5210340-A Reaction of hexachlorobutadiene with hydrogen fluoride BAYER AKTIENGESELLSCHAFT (DE) 1993-05-11 US disclosed
US-5146019-A Preparation of polyfluorobutenes BAYER AKTIENGESELLSCHAFT (DE) 1992-09-08 US disclosed
US-4391940-A POLYMERS/SHELL-CORE/ HOECHST AKTIENGESELLSCHAFT (DE) 1983-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190210945-A1 COMPOSITIONS CONTAINING 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) HCFC1, FGB, CYP2F1 PKM 4462/4885
US-10246389-B1 Compositions containing 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) HCFC1, FGB, CYP2F1 PKM 4462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.