Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456119 | 0.90 | PTGS2 (0.67) | PTGS2PTGS1ALDH1A1HPGDABCB11 | |
| SCHEMBL7466958 | 0.90 | PTGS2 (0.55) | PTGS2PTGS1ALDH1A1HPGDABCB11 | |
| SCHEMBL7465548 | 0.89 | PTGS2 (0.54) | PTGS2PTGS1ALDH1A1HPGDABCB11 | |
| SCHEMBL5698729 | 0.85 | PTGS2 (0.67) | PTGS2PTGS1ALDH1A1HPGD | |
| SCHEMBL5149168 | 0.84 | PTGS2 (0.51) | PTGS2PTGS1ALDH1A1ABCB11 | |
| SCHEMBL9206762 | 0.84 | PTGS2 (0.54) | PTGS2PTGS1ALDH1A1ABCB11 | |
| SCHEMBL7466137 | 0.83 | PTGS2 (0.68) | PTGS2PTGS1ALDH1A1ABCB11 | |
| SCHEMBL9210879 | 0.83 | PTGS2 (0.62) | PTGS2PTGS1ALDH1A1ABCB11 | |
| SCHEMBL3239886 | 0.82 | PTGS2 (0.77) | PTGS2PTGS1ALDH1A1ABCB11PDPK1 | |
| SCHEMBL5425139 | 0.82 | PTGS2 (0.83) | PTGS2PTGS1ALDH1A1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5550147-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTITHROMBOTIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0554829-A2 | Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |