Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 7/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527152 | 0.88 | IMPDH2 (0.47) | IMPDH2IGF1RSRCAXLPTK2 | |
| SCHEMBL1637371 | 0.82 | IMPDH2 (0.37) | IMPDH2IGF1RSRCAXLPTK2 | |
| SCHEMBL25342040 | 0.82 | IGF1R (0.36) | IMPDH2IGF1RSRCAXLPTK2 | |
| SCHEMBL4943759 | 0.82 | IMPDH2 (0.42) | IMPDH2IGF1RSRCAXLPTK2 | |
| SCHEMBL25341714 | 0.80 | CYP19A1 (0.37) | IMPDH2IGF1RSRCAXLPTK2 | |
| SCHEMBL23917711 | 0.78 | ERN1 (0.42) | IMPDH2IGF1RSRCAXLPTK2 | |
| SCHEMBL17109626 | 0.78 | ERN1 (0.42) | IMPDH2IGF1RSRCAXLPTK2 | |
| SCHEMBL9021987 | 0.78 | CYP19A1 (0.36) | IMPDH2IGF1RSRCAXLPTK2 | |
| SCHEMBL21929661 | 0.77 | MAOB (0.44) | IMPDH2IGF1RSRCAXLPTK2 | |
| SCHEMBL17660184 | 0.77 | IGF1R (0.43) | IMPDH2IGF1RSRCAXLPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624961-A | Benzylaminoethoxybenzene derivatives, production thereof and use thereof | JAPAN TOBACCO INC. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0693474-A1 | NOVEL BENZYLAMINOETHOXYBENZENE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Toyo Boseki Kabushiki Kaisha (JP) | 1996-01-24 | — | — | EP | disclosed |