Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694952 | 1.00 | MAPT (0.36) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL8689968 | 0.92 | MAPT (0.37) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL8922092 | 0.92 | MAPT (0.37) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL8921898 | 0.91 | ALDH1A1 (0.36) | MAPTALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL8696188 | 0.91 | ALDH1A1 (0.36) | MAPTALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL8923966 | 0.90 | ALDH1A1 (0.37) | MAPTALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL8693094 | 0.90 | ALDH1A1 (0.37) | MAPTALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL8923758 | 0.88 | ALDH1A1 (0.34) | MAPTALDH1A1HPGDRAB9AL3MBTL1 | |
| SCHEMBL8694615 | 0.88 | ALDH1A1 (0.34) | MAPTALDH1A1HPGDRAB9AL3MBTL1 | |
| SCHEMBL9202413 | 0.88 | ALDH1A1 (0.35) | MAPTALDH1A1HPGDSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641770-A | THIENAMYCINS ANTIBIOTICS | CHONG KUN DANG CORP. (KR) | 1997-06-24 | — | — | US | disclosed |