Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 6/20 | 0.77 |
| ▸ | ICMT | O60725 | 11/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926987 | 0.88 | PLA2G2A (0.68) | PLA2G2AICMTPPARGPPARDPPARA | |
| SCHEMBL7963252 | 0.87 | PLA2G2A (1.00) | PLA2G2AICMTMTNR1AMTNR1BPPARG | |
| SCHEMBL8926520 | 0.80 | PLA2G2A (0.74) | PLA2G2AICMTMTNR1AMTNR1B | |
| SCHEMBL8924312 | 0.79 | PLA2G2A (0.72) | PLA2G2AICMTMTNR1AMTNR1BPPARG | |
| SCHEMBL7965222 | 0.78 | PLA2G2A (0.81) | PLA2G2AICMTPPARGPPARDPPARA | |
| SCHEMBL7953321 | 0.78 | PLA2G2A (1.00) | PLA2G2AICMTPPARGPPARDPPARA | |
| SCHEMBL20769739 | 0.78 | PLA2G2A (0.83) | PLA2G2AICMTMTNR1AMTNR1BPPARG | |
| SCHEMBL8926059 | 0.78 | PLA2G2A (0.71) | PLA2G2AICMTMTNR1AMTNR1BPPARG | |
| SCHEMBL7965309 | 0.78 | PLA2G2A (1.00) | PLA2G2AICMT | |
| SCHEMBL7961582 | 0.78 | PLA2G2A (0.81) | PLA2G2AICMTPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684034-A | INHIBITORS OF HUMAN NON-PANCREATIC SECRETORY PHOSPHOLIPASE A2, TREATMENT OF SEPTIC SHOCK, TRAUMA, RESPIRATORY DISORDERS, RHEUMATIC ARTHRITIS, INHIBITORS OF ARACHIDONIC ACID RELEASE | ELI LILLY AND COMPANY (US) | 1997-11-04 | — | — | US | disclosed |