SCHEMBL8924313

SCHEMBL8924313

C[C](C)CC(=O)OC(C)(C)Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSK P43235 2/20 0.47
MMP8 P22894 4/20 0.43
ALDH1A1 P00352 3/20 0.43
RECQL P46063 2/20 0.43
CYP3A4 P08684 4/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
CYP2D6 P10635 2/20 0.42
LMNA P02545 2/20 0.42
ATM Q13315 1/20 0.42
CYP1A2 P05177 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
NFKB1 P19838 1/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
MAPK1 P28482 1/20 0.40
SLC6A2 P23975 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20349661 0.87 CTSK (0.47) CTSKMMP8ALDH1A1RECQLCYP3A4
SCHEMBL3833989 0.86 TSHR (0.51) CTSKALDH1A1RECQLCYP3A4CYP2C9
SCHEMBL872678 0.83 KCNH2 (0.51) CTSKMMP8ALDH1A1RECQLCYP3A4
SCHEMBL111212 0.82 ALDH1A1 (0.50) CTSKMMP8ALDH1A1RECQLCYP3A4
SCHEMBL5556046 0.81 CYP3A4 (0.49) CTSKMMP8ALDH1A1RECQLCYP3A4
SCHEMBL1003605 0.80 CTSK (0.49) CTSKMMP8ALDH1A1RECQLCYP3A4
SCHEMBL1003604 0.80 CTSK (0.49) CTSKMMP8ALDH1A1RECQLCYP3A4
SCHEMBL273935 0.80 CTSK (0.50) CTSKMMP8ALDH1A1RECQLCYP3A4
SCHEMBL27484992 0.80 CTSK (0.50) CTSKMMP8ALDH1A1RECQLCYP3A4
SCHEMBL9611177 0.79 CTSK (0.42) CTSKMMP8ALDH1A1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5639770-A SUPEROXIDE INHIBITOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-06-17 US disclosed
EP-0600092-A1 THIAZOLE DERIVATIVE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-06-08 EP disclosed