Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.59 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | BMP1 | P13497 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9235992 | 0.85 | CYP4F2 (0.63) | CYP4A11CYP4F2RAB9AKMT2AL3MBTL1 | |
| SCHEMBL13230897 | 0.77 | CYP4A11 (0.72) | CYP4A11CYP4F2KMT2AMEN1HPGD | |
| SCHEMBL70185 | 0.76 | CYP4A11 (0.75) | CYP4A11CYP4F2KMT2AMEN1HPGD | |
| SCHEMBL2404460 | 0.75 | CYP4A11 (0.73) | CYP4A11CYP4F2RAB9ALOXL2NPC1 | |
| SCHEMBL12176878 | 0.75 | CYP4A11 (0.70) | CYP4A11CYP4F2RAB9AHPGDLOXL2 | |
| SCHEMBL2222434 | 0.75 | SMN1; SMN2 (0.60) | RAB9AL3MBTL1HPGDTRPV1NPC1 | |
| SCHEMBL10609552 | 0.75 | CYP4A11 (0.74) | CYP4A11CYP4F2KMT2AMEN1HPGD | |
| SCHEMBL2654777 | 0.75 | CYP4A11 (1.00) | CYP4A11CYP4F2HPGDLOXL2MAPT | |
| SCHEMBL1792416 | 0.75 | CYP4A11 (0.74) | CYP4A11CYP4F2RAB9AHPGDLOXL2 | |
| SCHEMBL1446036 | 0.74 | CYP4A11 (0.68) | CYP4A11CYP4F2KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| EP-0685466-A1 | 3-Heteroaliphatyle-and 3-hetero-(aryle)-aliphatyle-2(1H)-quinolone derivatives | CIBA-GEIGY AG (CH) | 1995-12-06 | — | — | EP | disclosed |